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CAS No. 93118-03-7 | 2-CHLORO-3-(TRIFLUOROMETHYL)BENZALDEHYDE

CAS No. 93118-03-7 | 2-CHLORO-3-(TRIFLUOROMETHYL)BENZALDEHYDE

Name: 2-CHLORO-3-(TRIFLUOROMETHYL)BENZALDEHYDE CAS No. 93118-03-7 MF:C8H4ClF3O MW:208.57 Purity:95% Package: 10g,25g,50g,100g,250g Worldwide Delivery

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Product introduction

Introduction and application of CAS No. 93118-03-7 | 2-CHLORO-3-(TRIFLUOROMETHYL)BENZALDEHYDE

Synonyms:TIMTEC-BBSBB003469;

2-Chloro-3-(trifluoromethyl)benzaldehyde98%;

2-Choro-3-(trifluoroMethyl)benzaldehyde;

2-Fluoro-4-hydroxybenzonitrile;

Benzaldehyde,2-chloro-3-(trifluoromethyl)-;

2-CHLORO-3-(TRIFLUOROMETHYL)BENZALDEHYDEISO9001：2015REACH

Specification:

ITEMS	SPECIFICATION
CAS	93118-03-7
MF	C8H4ClF3O
MW	208.57
Melting point	37-43 °C
Boiling point	216.6±35.0 °C
Density	1.423±0.06 g/cm3
Flash point	>230 °F
Color	White to off white
Form	crystal or powder
Storage condition	under inert gas (nitrogen or Argon) at 2-8°C

use:

2-Chloro-3-(trifluoromethyl)benzaldehyde can be used as an organic synthesis intermediate. It can be prepared by the reaction of 2-trifluoromethyl-chlorobenzene and n-butyllithium. It can be used to prepare pharmaceutical intermediates (2-chloro- 3-Trifluoromethylbenzyl)cyclopropylamine.

preparation:

To a solution of 2-trifluoromethyl-chlorobenzene (50.0 g, 277 mmol) in THF (500 mL) at -70°C was added BuLi (1.6 M in hexane, 173 mL, 277 mmol). The solution was stirred at -70°C for 2 hours and a solution of DMF (21.3 mL, 277 mmol) in THF (100 mL) was added. The mixture was allowed to warm to room temperature overnight. Water (200 ml) was added and the mixture was extracted with Et2O (2x). The combined organic extracts were dehydrated over magnesium sulfate, filtered and the solvent was removed under reduced pressure. The residue was purified by column chromatography (heptane/EtOAc 20:1) to yield the title compound 2-chloro-3-(trifluoromethyl)benzaldehyde (37.4 g, 65%). LC-MS: tR=0.96 minutes.

Package and transportation :

Package: 10g,25g,50g,100g,250g